At present, digital currency has been increasingly exploited as a means to gain a benefit from victims of crime by criminals, both in the form of requesting victims to transfer their digital currency directly and the money laundering through digital currency. The criminals often use digital currency as a leverage due to its intangibility and transferability via Blockchain without a third party. This way, the identity of transferor and transferee may remain undisclosed. Criminals can conceal their identities while conducting transactions of digital currency. Such nature creates great difficulties for law enforcement officials because they are unable to enforce the measures on examining and confiscating exhibits as provided in the Criminal Procedure Code, the application of which is restricted to physical exhibits. The problem has raised concerns and difficulties for law enforcement officials around the world. This causes the United Nations Office on Drugs and Crime (UNODC) to produce the Basic Manual on the Detection and Investigation of the Laundering of Crime Proceeds Using Virtual Currencies, a prototype manual of investigating cases in which criminals use digital currency as a part of offense. This article aims to study the examination and confiscation of digital currency in criminal cases in response to the UNODC guidelines for the benefit of law enforcement in Thailand.